SUPEROXIDE DISMUTASE (SOD) LEVELS IN RAT BRAIN AFTER HeNe LASER IRRADIATION COMPARED TO INTRAVENOUS ADMINISTRATION OF SOD SOLUTION: AN EXPERIMENTAL MODEL FOR THE PREVENTION OF CEREBRAL VASOSPASM AFTER SUBARACHNOID HAEMORRHAGE
نویسندگان
چکیده
منابع مشابه
Gene transfer of extracellular superoxide dismutase failed to prevent cerebral vasospasm after experimental subarachnoid hemorrhage.
BACKGROUND AND PURPOSE We examined the therapeutic effect of human extracellular superoxide dismutase (ECSOD) gene transfer in the prevention of delayed cerebral vasospasm after experimental subarachnoid hemorrhage (SAH) because it was reported ECSOD relieved early-stage vasospasm. METHODS Twenty mongrel dogs were divided randomly into 4 groups to serve as control, SAH, SAH+adenovirus ECSOD (...
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چکیده ندارد.
Overexpressing Extracellular Superoxide Dismutase Attenuation of Cerebral Vasospasm After Subarachnoid Hemorrhage in Mice
Matthew J. McGirt, Augusto Parra, Huaxin Sheng, Yoshinori Higuchi, Tim D. Oury, Daniel T. Overexpressing Extracellular Superoxide Dismutase Attenuation of Cerebral Vasospasm After Subarachnoid Hemorrhage in Mice Print ISSN: 0039-2499. Online ISSN: 1524-4628 Copyright © 2002 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Aven...
متن کاملAttenuation of cerebral vasospasm after subarachnoid hemorrhage in mice overexpressing extracellular superoxide dismutase.
BACKGROUND AND PURPOSE Subarachnoid hemorrhage (SAH) increases production of vascular extracellular superoxide anion (*O2-). We examined whether overexpression of murine extracellular superoxide dismutase (EC-SOD) alters SAH-induced cerebral vasospasm, oxidative stress, and neurological outcome. METHODS Mice exhibiting a 2-fold increase in vascular EC-SOD and wild-type (WT) littermates were s...
متن کاملSuperoxide levels and function of cerebral blood vessels after inhibition of CuZn-SOD.
The goal of this study was to examine the role of endogenous copper/zinc (CuZn)-superoxide dismutase (SOD) on superoxide levels and on responses of cerebral blood vessels to stimuli that are mediated by nitric oxide (acetylcholine) and cyclooxygenase-dependent mechanisms (bradykinin and arachidonic acid). Levels of superoxide in the rabbit basilar artery were measured using lucigenin-enhanced c...
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ژورنال
عنوان ژورنال: LASER THERAPY
سال: 1991
ISSN: 0898-5901,1884-7269
DOI: 10.5978/islsm.91-or-25